PAM 250

---

Biochemical properties of the amino acids
C	sulfhydryl	S, T, P, A, G	small or hydrophylic	N, D, E, Q	acidic, amide side chains
H, R, K	basic	M, I, L, V	hydrophobic	F, W, Y	aromatic

	C	S	T	P	A	G	N	D	E	Q	H	R	K	M	I	L	V	F	Y	W
C	12
S	0	2
T	-2	1	3
P	-3	1	0	6
A	-2	1	1	1	2
G	-3	1	0	-1	1	5
N	-4	1	0	-1	0	0	2
D	-5	0	0	-1	0	1	2	4
E	-5	0	0	-1	0	0	1	3	4
Q	-5	-1	-1	0	0	-1	1	2	2	4
H	-3	-1	-1	0	-1	-2	2	1	1	3	6
R	-4	0	-1	0	-2	-3	0	-1	-1	1	2	6
K	-5	0	0	-1	-1	-2	1	0	0	1	0	3	5
M	-5	-2	-1	-2	-1	-3	-2	-3	-2	-1	-2	0	0	6
I	-2	-1	0	-2	-1	-3	-2	-2	-2	-2	-2	-2	-2	2	5
L	-6	-3	-2	-3	-2	-4	-3	-4	-3	-2	-2	-3	-3	4	2	6
V	-2	-1	0	-1	0	-1	-2	-2	-2	-2	-2	-2	-2	2	4	2	4
F	-4	-3	-3	-5	-4	-5	-4	-6	-5	-5	-2	-4	-5	0	1	2	-1	9
Y	0	-3	-3	-5	-3	-5	-2	-4	-4	-4	0	-4	-4	-2	-1	-1	-2	7	10
W	-8	-2	-5	-6	-6	-7	-4	-7	-7	-5	-3	2	-3	-4	-5	-2	-6	0	0	17
	C	S	T	P	A	G	N	D	E	Q	H	R	K	M	I	L	V	F	Y	W

Biochemical properties of the amino acids
C	sulfhydryl	S, T, P, A, G	small or hydrophylic	N, D, E, Q	acidic, amide side chains
H, R, K	basic	M, I, L, V	hydrophobic	F, W, Y	aromatic

---

Last modified: November 22nd, 2010.
Maintained by Dannie Durand (durand@cs.cmu.edu), Sunguk Choi and Annette McLeod.