Back to "Biological Language Modeling Seminar Topics"

General reference: Ref_JianEtal Chapter 16

Protein dynamics

A protein's dynamic properties can be crucial for its function:

Kay 1998

Zidek et al. 1999

Forman-Kay 1999

Conformational distribution and fluctuations in a protein's denatured state are important for native thermodynamic stability

Wu 1931

Dill 1990

Edsall 1995

Shortle 1996

Understand tendency to adopt disease-causing misfolded and/or aggregated forms by study of dynamics of unfolded states:

Cohen and Prusiner 1998

Kelley 1998

Dobson 1999