0. DOCID:19688 SCORE: 0.000560713286875255
DOCNO: 1729088
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: adverse effects
QUALIFIER: chemically induced
QUALIFIER: drug therapy
QUALIFIER: blood
AUTHOR: S Hayashi S
AUTHOR: H Ogino H
AUTHOR: K Ogata K
AUTHOR: K Yagawa K
AFFILIATION: Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Chest.
COUNTRY: UNITED STATES
TITLE: Hypercoagulopathy induced by chemotherapy in a patient with lung cancer. A possible role for a factor with thrombosis-inducing activity (TIA).
PUBDATE: 19920101
We treated a patient with lung cancer in whom a hypercoagulopathy was induced acutely by chemotherapy. He received systemic chemotherapy twice and in both instances developed disseminated intravascular coagulopathy (DIC), accompanied by acute decrements of the peripheral platelet count and plasma fibrinogen, an increment of the fibrin degradation products (FDP), and bleeding tendency with the appearance of skin purpura. In each instance, the plasma thrombosis-inducing activity (TIA) appeared one to three days after chemotherapy and subsided subsequently.

1. DOCID:18888 SCORE: 0.000560665862980805
DOCNO: 1655209
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secretion
QUALIFIER: secretion
QUALIFIER: complications
QUALIFIER: secretion
QUALIFIER: complications
AUTHOR: K Shimizu K
AUTHOR: S Nakano S
AUTHOR: Y Nakano Y
AUTHOR: M Ando M
AUTHOR: K Seki K
AUTHOR: N Kameda N
AFFILIATION: Tokyo Rosai Hospital, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Ectopic atrial natriuretic peptide production in small cell lung cancer with the syndrome of inappropriate antidiuretic hormone secretion.
PUBDATE: 19911101
One autopsy case with small cell lung cancer and the syndrome of inappropriate antidiuretic hormone secretion (SIADH) is reported. Both plasma atrial natriuretic peptide (ANP) and arginine vasopressin (AVP) levels were high, and the presence of significantly high levels of ANP and AVP in tumor tissue was confirmed by gel chromatography and radioimmunoassay techniques. To the best of the authors' knowledge, this is the first case in which ectopic ANP production and its secretion into blood (leading to SIADH) were proved.

2. DOCID:18395 SCORE: 0.000560509920807189
DOCNO: 8414625
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: therapeutic use
AUTHOR: R P Salvadori RP
AUTHOR: D Rembado D
AUTHOR: R Serrato R
AFFILIATION: Health Physics Service, S. Corona Hospital, Pietra Ligure Savona, Italy.
PUBTYPE: Journal Article
JOURNALTITLE: Panminerva medica.
COUNTRY: ITALY
TITLE: Proton-therapy, present status.
PUBDATE: 19930601
At the moment, proton-therapy is the most advanced radiotherapeutic technique in cancer treatment. The use of the high energy proton beam (from 70 MeV to 200 MeV) lets a Bragg's peak be moved to different depths, so allowing personal radiotherapeutic treatment. In recent years, many proton-therapy centers have grown up throughout the world with very satisfactory clinical results, first of all in eye melanoma treatment. The future expectations are very promising, even if the very high installation and maintenance expenses of a synchrotron (for proton production) hinder the development of such a method.

3. DOCID:16845 SCORE: 0.000559478327046486
DOCNO: 1762261
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: diagnosis
QUALIFIER: analysis
AUTHOR: Y Saito Y
AFFILIATION: Department of Urology, Nagasaki University School of Medicine.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nippon Hinyōkika Gakkai zasshi. The japanese journal of urology.
COUNTRY: JAPAN
TITLE: [Acid phosphatase as tumor marker of prostatic cancer]
PUBDATE: 19911101
Prostatic cancer was the first malignancy in which tumor markers could be used to follow the response to therapy or progression of the prostate cancer. The use of these tumor markers has been of significant clinical value in diagnosis and follow-up of patients. Over the years, significant technical improvements have been made on the sensitivity and specificity of the assays for prostatic acid phosphatase.

4. DOCID:16714 SCORE: 0.000558759565842339
DOCNO: 1410063
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mass Screening
QUALIFIER: diagnosis
QUALIFIER: prevention & control
AUTHOR: P D Shenefelt PD
AFFILIATION: Department of Internal Medicine, College of Medicine, University of South Florida, Tampa.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Primary care.
COUNTRY: UNITED STATES
TITLE: Skin cancer prevention and screening.
PUBDATE: 19920901
Prevention and early detection of skin cancers are crucial to reducing morbidity and mortality. Armed with the above information and with some experience, the primary care physician can understand risk factors and recognize common benign and malignant skin tumors. This allows the primary care physician to play a key role in teaching patients about skin cancer prevention and in screening patients for skin cancers.

5. DOCID:16737 SCORE: 0.000558182426869505
DOCNO: 2253738
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: mortality
AUTHOR: G Saltalamacchia G
AUTHOR: F La Rosa F
AUTHOR: F Pannelli F
AFFILIATION: Dipartimento di Scienze igienistiche e sanitarie-ambientali, Università di Camerino.
PUBTYPE: Journal Article
JOURNALTITLE: European journal of epidemiology.
COUNTRY: ITALY
TITLE: Parallelism in the mortality clustering of the most frequent cancer sites in Italy and in the Marche region.
PUBDATE: 19900901
Clusters of selected cancer sites mortality, regarding Italy and the Marche region, were compared. Very similar associations were found both in males and in females, in particular between the alcohol-tobacco-related sites. Many clusters agree with the international literature, while others could constitute a starting point for formulating new hypotheses.

6. DOCID:16749 SCORE: 0.000558182423878505
DOCNO: 1500391
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: R F Ozols RF
AFFILIATION: Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Hematology/oncology clinics of North America.
COUNTRY: ENGLAND
TITLE: Chemotherapy for advanced epithelial ovarian cancer.
PUBDATE: 19920801
In the past decade there have been significant improvements in chemotherapy for advanced ovarian cancer. Platinum-based chemotherapy has improved response rates and, to a lesser degree, prolonged survival. Taxol and its combination with platinum drugs holds the promise for even further improvements in survival. Clinical trials are evaluating issues such as dose-intensity, new combinations, and drug resistance.

7. DOCID:18781 SCORE: 0.000557468284236747
DOCNO: 1303888
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: methods
AUTHOR: A Kovács A
AUTHOR: G Kiss G
AUTHOR: A Fehér A
AUTHOR: M Roszik M
AUTHOR: A Kovács A
AFFILIATION: Szent-Györgyi Albert Orvostudományi Egyetem, Fogászati és Szájsebészeti Klinika.
PUBTYPE: Journal Article
JOURNALTITLE: Fogorvosi szemle.
COUNTRY: HUNGARY
TITLE: [Free radial forearm flap in the reconstruction of the mouth floor after removal of a tumor by pull-through method]
PUBDATE: 19920901
Free radial forearm flap was used to replace the tissue defect caused by pull-through operation for cancer of the mouth in 13 cases. There was no total or partial flap failure. The greatest advantage of the method is that the restriction of the tongue movement is less when compared to the results of other methods since the thin forearm flaps are well adaptable and are of a pliable nature. The newly developed lower alveolar crest makes the prosthetic rehabilitation possible.

8. DOCID:18269 SCORE: 0.000557439772715895
DOCNO: 1876588
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Environmental Exposure
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: adverse effects
QUALIFIER: adverse effects
AUTHOR: D Schmähl D
AFFILIATION: Institut für Toxikologie und Chemotherapie, Deutsches Krebsforschungszentrum, Heidelberg.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Pneumologie (Stuttgart, Germany)
COUNTRY: GERMANY
TITLE: [Etiology of bronchial cancer: smoking, passive smoking, environment and occupation]
PUBDATE: 19910401
The inhaled tobacco smoke is the most important determinant in the etiology of lung cancer and there is a clear dose-effect relation between lung cancer risk and the duration of smoking, the number of cigarettes and the intensity of inhalation. The opinions about lung cancer risk from passive smoking are divided and the published data are still in discussion. Occupational substances include chromates, nickel, beryllium, alkylated compounds, vinylchloride, arsenic compounds and in particular asbestos. Fortunately air pollution has no or small part in the etiology of lung cancer.

9. DOCID:16856 SCORE: 0.000451356937197038
DOCNO: 2225449
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: etiology
QUALIFIER: complications
QUALIFIER: complications
AUTHOR: J H Avashia JH
AUTHOR: T D Walsh TD
AUTHOR: A J Thomas AJ
AUTHOR: M Kaye M
AUTHOR: A Licata A
AFFILIATION: Department of Hematology and Medical Oncology, Cleveland Clinic Foundation, Ohio 44195-5236.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Cleveland Clinic journal of medicine.
COUNTRY: UNITED STATES
TITLE: Metastatic carcinoma of the prostate with hypercalcemia.
PUBDATE: 19901001
A patient presented with advanced cancer of the prostate and underwent bilateral orchiectomy. After 2 years, hypercalcemia developed and was managed successfully with saline diuresis, furosemide, and oral glucocorticoid therapy. It is believed that the patient's hypercalcemia was caused by a metabolic complication of progressive, advanced disease.

10. DOCID:18588 SCORE: 0.000249294320896995
DOCNO: 1964403
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: microbiology
QUALIFIER: isolation & purification
QUALIFIER: microbiology
QUALIFIER: microbiology
QUALIFIER: analysis
AUTHOR: L Jin L
AFFILIATION: Institute of Basic Medical Sciences, Academy of Military Medical Sciences, Beijing.
PUBTYPE: Journal Article
JOURNALTITLE: Zhonghua bing li xue za zhi Chinese journal of pathology.
COUNTRY: CHINA
TITLE: [Detection of HBxAg in liver specimens of patients with hepatocellular carcinoma]
PUBDATE: 19901201
Detection of HBxAg was done by the immunogold-silver staining technique in 22 liver cancer specimens from patients with hepatocellular carcinoma and positive markers of hepatitis B were found to express HBxAg of hepatitis B virus, which was distributed in the perinuclear cytoplasm. The result suggests that HBxAg can be detected practically in all the liver specimens of the patients with hepatocellular carcinoma, who had been infected by hepatitis B virus. The relationship between X gene and its translation product and hepatocellular carcinoma is discussed.

11. DOCID:18645 SCORE: 0.000249277794313264
DOCNO: 1605652
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: M Ogawa M
AFFILIATION: Aichi Cancer Center, Nagoya, Japan.
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Chemotherapy of advanced breast cancer]
PUBDATE: 19920601
The frontline chemotherapy for advanced breast cancer has been either CMF or CAF and the combinations can obtain an overall response rate exceeding 50%, including complete responses of 10-15% and median survival times of 12-18 months. Complete responders have survived longer than patients with partial responses or stable diseases. Consequently, high dose chemotherapy with autologous bone marrow transplantation has been investigated in order to obtain more complete responses and ultimately to obtain a cure in patients responding to induction chemotherapy. Seventeen to 30% of patients who became complete responses have maintained continuously complete responders. Taxol and CI941 are promising agents under investigation.

12. DOCID:16003 SCORE: 0.000249276905830474
DOCNO: 1826844
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: methods
AUTHOR: R Karel-Brant R
PUBTYPE: Journal Article
JOURNALTITLE: Dermatology nursing / Dermatology Nurses' Association.
COUNTRY: UNITED STATES
TITLE: Periorbital skin cancers.
PUBDATE: 19910401
Mohs surgery is an excellent treatment for removal of periorbital skin cancers. Important structures and surrounding tissue may be preserved with this technique.

13. DOCID:19587 SCORE: 0.000249276100316778
DOCNO: 1736473
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Genital Neoplasms, Male
DESCRIPTOR: Penile Neoplasms
DESCRIPTOR: Precancerous Conditions
DESCRIPTOR: Scrotum
AUTHOR: P F Schellhammer PF
AUTHOR: G H Jordan GH
AUTHOR: E L Robey EL
AUTHOR: J T Spaulding JT
AFFILIATION: Department of Urology, Eastern Virginia Medical School, Norfolk.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Urologic clinics of North America.
COUNTRY: UNITED STATES
TITLE: Premalignant lesions and nonsquamous malignancy of the penis and carcinoma of the scrotum.
PUBDATE: 19920201
Premalignant lesions of the penis include cutaneous horn, balanitis xerotica obliterans, and leukoplakia. The true incidence of progression of each of these to squamous-cell carcinoma is unknown. Bowenoid papulosis, erythroplasia of Queyrat, and Bowen's disease are histologically identical to in situ carcinoma. Although the first is consistently benign, the latter two regularly evolve into invasive cancer. Malignant scrotal lesions include squamous-cell carcinoma, liposarcoma, leiomyosarcoma, basal-cell carcinoma, extramammary Paget's disease, erythroplasia of Queyrat, malignant melanoma, and metastases. Hemangioma can be confused with carcinoma.

14. DOCID:19300 SCORE: 0.000249274166417165
DOCNO: 8094712
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Gene Amplification
QUALIFIER: genetics
QUALIFIER: genetics
QUALIFIER: therapeutic use
AUTHOR: U Lönn U
AUTHOR: S Lönn S
AUTHOR: B Stenkvist B
AFFILIATION: Radiumhemmet, Karolinska Hospital, Stockholm, Sweden.
PUBTYPE: Journal Article
JOURNALTITLE: International journal of cancer. Journal international du cancer.
COUNTRY: UNITED STATES
TITLE: Reduced occurrence of mdr-1 amplification in stage-IV breast-cancer patients treated with tamoxifen compared with other endocrine treatments.
PUBDATE: 19930201
Amplification of mdr-1 occurs in breast cancer patients receiving endocrine treatment. We have compared a group of patients receiving tamoxifen and a group receiving second-line endocrine treatment after failure of tamoxifen treatment. Chronological tumor samples were obtained by fine-needle biopsies from the same tumor lesion of each patient and PCR was used to detect the appearance of gene amplification. Three of 20 patients receiving tamoxifen developed amplified mdr-1 whereas 7 of 17 patients receiving second-line endocrine treatment developed mdr-1 amplification.