0. DOCID:19801 SCORE: 0.00583465533009774
DOCNO: 1561266
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mammaplasty
QUALIFIER: radiotherapy
AUTHOR: N Handel N
AUTHOR: B Lewinsky B
AUTHOR: J R Waisman JR
AFFILIATION: Breast Center, Van Nuys, Calif. 91405.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Plastic and reconstructive surgery.
COUNTRY: UNITED STATES
TITLE: Reduction mammaplasty following radiation therapy for breast cancer.
PUBDATE: 19920501
This report describes an unusual case in which reduction mammaplasty was performed following radiation therapy for breast cancer. While healing was significantly prolonged (compared with the nonirradiated contralateral breast), the final result was satisfactory from both the functional and the aesthetic standpoint. Women with prior radiation therapy may be considered candidates for reduction mammaplasty. Patients should be warned of the increased risks of wound complications, the likelihood of delayed healing, and the possibility of pigmentation changes in the grafted nipple-areola complex. We elected to transpose the nipple as a full-thickness graft, but consideration also might be given to use of an inferiorly based pedicle flap.

1. DOCID:27348 SCORE: 0.00529479092111998
DOCNO: 11163152
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Oligonucleotide Array Sequence Analysis
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: P L Porter PL
AFFILIATION: Divisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, and Department of Pathology, University of Washington Medical Center, 1100 Fairview N, Seattle, Washington 98109, USA. pporter@fhcrc.org
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in genetics & development.
COUNTRY: England
TITLE: Molecular markers of tumor initiation and progression.
PUBDATE: 20010201
Of the hundreds of genes and proteins reported to be altered in human cancers, only a few are sufficiently central to warrant translation into diagnostic or therapeutic tools. Three recent developments have the potential to alter radically the discovery of molecular markers: the compendium of human genes; the advent of technologies that provide the means to identify simultaneously several known and unknown genes and proteins; and an appreciation of the critical processes involved in tumor initiation and progression.

2. DOCID:29548 SCORE: 0.00503178589669696
DOCNO: 15582892
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: Marc Galiano M
AUTHOR: Fabrice Dugardin F
AUTHOR: François Rozet F
AUTHOR: Xavier Cathelineau X
AUTHOR: Guy Vallancien G
AFFILIATION: Institut mutualiste Montsouris, Université René-Descartes Paris V, 42 boulevard Jourdan, 75674 Paris cedex 14.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Bulletin du cancer.
COUNTRY: France
TITLE: [The surgical management of recurrent urological malignancies after primary ablative therapy]
PUBDATE: 20041101
This literature review highlights the surgical management of recurrent urological malignancies after primary ablative therapy. In particular, recurrent nonseminomatous germ cell tumours (NSGCT) post-chemotherapy, recurrent bladder cancer post-cystectomy, loco-regional recurrence of prostate cancer after radiotherapy, and loco-regional recurrence of renal cell carcinoma after radical nephrectomy. The indications, operative technique, complications and outcomes of each malignancy are discussed.

3. DOCID:31471 SCORE: 0.0042250177937737
DOCNO: 12063827
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Infusions, Intra-Arterial
QUALIFIER: drug therapy
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
AUTHOR: Matthias Lorenz M
AUTHOR: Stefan Heinrich S
AFFILIATION: Department of General and Vascular Surgery, University Hospital of Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany. M.Lorenz@em.uni-frankfurt.de
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Hematology/oncology clinics of North America.
COUNTRY: United States
TITLE: Regional chemotherapy.
PUBDATE: 20020201
Regional chemotherapy is an interesting treatment option in patients with advanced pancreatic cancer but cannot be considered standard treatment, and it should not be performed outside controlled clinical trials. The real value of regional chemotherapy must be evaluated in larger, randomized trials. New drug combinations may reduce the observed side effects and improve tumor response. Gene therapy with p53 and K-ras modulated herpesviruses may become a palliative treatment option and can be administered easily by regional chemotherapy techniques [23].

4. DOCID:31023 SCORE: 0.00422491139190602
DOCNO: 16050939
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug effects
QUALIFIER: pharmacology
AUTHOR: Susan G Lakoski SG
AUTHOR: David M Herrington DM
AFFILIATION: Department of Internal Medicine/Cardiology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Diabetes, obesity & metabolism.
COUNTRY: England
TITLE: Effects of oestrogen receptor-active compounds on lipid metabolism.
PUBDATE: 20050901
Selective estrogen receptor modulators (SERMs) have been used successfully in the treatment of breast cancer and osteoporosis while Tibolone has been used extensively in Europe for the treatment of menopausal symptoms. Limited data is available on the effect of these agents on the cardiovascular system. Traditional and novel lipid markers are valuable in determining patients at increased cardiovascular risk. The purpose of this article is to discuss the mechanism of action of Tamoxifen, Raloxifene and Tibolone and their effects on lipid metabolism.

5. DOCID:22913 SCORE: 0.00422217551554887
DOCNO: 7578386
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: methods
AUTHOR: P Rossi P
AUTHOR: M Bezzi M
AFFILIATION: Department of Radiology, University of Rome La Sapienza, Policlinico Umberto I, Italy.
PUBTYPE: Journal Article
JOURNALTITLE: Current opinion in oncology.
COUNTRY: UNITED STATES
TITLE: Interventional radiology in gastrointestinal neoplasms.
PUBDATE: 19950701
Interventional radiology plays a significant role in different fields of gastrointestinal oncology. Percutaneous techniques can be used to diagnose and stage bile duct and pancreatic cancer. Palliation of esophageal tumors and malignant biliary obstruction may be achieved with interventional techniques, whereas curative attempts are directed mainly towards primary and secondary liver tumors. The therapeutic potential of interventional radiology is still expanding, as are all other forms of minimally invasive therapy. This article reviews the relevant contributions on this subject that have appeared in the past year. The introduction of new techniques is described, and the results of clinical studies are discussed.

6. DOCID:31899 SCORE: 0.0040929514514484
DOCNO: 14702915
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Nurse's Role
QUALIFIER: complications
QUALIFIER: psychology
QUALIFIER: standards
QUALIFIER: standards
QUALIFIER: nursing
AUTHOR: James R Zabora JR
AUTHOR: Matthew J Loscalzo MJ
AUTHOR: Jason Weber J
AFFILIATION: National Catholic School of Social Service, Catholic University of America, 620 Michigan Ave, 102 Shahan Hall, Washington, DC 20064, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in oncology nursing.
COUNTRY: United States
TITLE: Managing complications in cancer: identifying and responding to the patient's perspective.
PUBDATE: 20031101
OBJECTIVES: To describe psychosocial problems experienced by cancer patients and present assessment tools to evaluate these issues and develop effective management programs. DATA SOURCES: Published literature and clinical experience. CONCLUSION: A screening program may identify patients needing psychologic evaluation and treatment and reduce distress for patients and caregivers. IMPLICATIONS FOR NURSING PRACTICE: Use of screening tools allows critical decisions to be made regarding treatment for patients with high levels of distress, fatigue, and other conditions.

7. DOCID:30694 SCORE: 0.00405447519908823
DOCNO: 16311648
OWNER: NLM
STATUS: In-Process
AUTHOR: Faris Q Alenzi FQ
AFFILIATION: Department of Medical Laboratory Sciences, College of Applied Medical Sciences, King Faisal University, PO Box 2114, Dammam 31451, Kingdom of Saudi Arabia. faris_alenzi@hotmail.com
PUBTYPE: Journal Article
JOURNALTITLE: Saudi medical journal.
COUNTRY: Saudi Arabia
TITLE: Apoptosis and diseases: regulation and clinical relevance.
PUBDATE: 20051101
It is increasingly clear that apoptosis plays a central role in the pathogenesis of several human diseases. For instance, an increase in apoptosis leads to cell loss accompanied by neurodegenerative diseases, whereas we know that genetically determined defects of apoptosis result in deregulated cell proliferation, typical of cancer. Hence, apoptosis may be relevant as therapeutic targets for many human diseases. This article reviews briefly the regulation and the clinical relevance of apoptotic mechanisms in several different human diseases.

8. DOCID:30599 SCORE: 0.00405447438222321
DOCNO: 15875146
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: methods
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: methods
QUALIFIER: surgery
QUALIFIER: methods
AUTHOR: J R Siewert JR
AUTHOR: H Bartels H
AUTHOR: H J Stein HJ
AFFILIATION: Chirurgische Klinik und Poliklinik, Klinikum rechts der Isar der TU München.
PUBTYPE: Journal Article
JOURNALTITLE: Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen.
COUNTRY: Germany
TITLE: [Abdomino-right-thoracic esophagectomy with intrathoracic anastomosis in Barrett's cancer]
PUBDATE: 20050601
The modified technique of abdomino-right-thoracic esophagectomy (the Lewis-Tanner approach) is increasingly being favoured as the surgical procedure of choice in patients with resectable adenocarcinoma of the distal esophagus, so-called Barrett's cancer. The technical details of this procedure and the reconstruction of gastrointestinal continuity using a gastric tube with high intrathoracic anastomosis are illustrated, as they have proved useful in our own practice during recent years.

9. DOCID:22740 SCORE: 0.00399348359808298
DOCNO: 7742518
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Laparoscopy
QUALIFIER: surgery
AUTHOR: J M Childers JM
AUTHOR: A Nasseri A
AFFILIATION: Department of Obstetrics and Gynecology, University of Arizona, Tucson, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in obstetrics & gynecology.
COUNTRY: UNITED STATES
TITLE: Minimal access surgery in gynecologic cancer: we can, but should we?
PUBDATE: 19950201
Operative laparoscopists continue to refine surgical techniques applicable to patients with gynecologic malignancies. Various techniques for radical hysterectomy and larger series of patients with endometrial cancer have now been reported. The technical feasibility of such operations is being established. Although oncologic patients may enjoy the known benefits of laparoscopic surgery, such as shorter hospitalization, the known shortcomings, such as longer operative times and increased cost, are a concern. The unknown shortcomings and the unknown overall survival of laparoscopically managed patients continue to keep the majority of oncologic surgeons a safe distance away.

10. DOCID:20969 SCORE: 0.00390577742812919
DOCNO: 7821417
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Oxidative Stress
QUALIFIER: metabolism
QUALIFIER: metabolism
AUTHOR: S Toyokuni S
AUTHOR: K Okamoto K
AUTHOR: J Yodoi J
AUTHOR: H Hiai H
AFFILIATION: Department of Pathology, Faculty of Medicine, Kyoto University, Japan.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: FEBS letters.
COUNTRY: NETHERLANDS
TITLE: Persistent oxidative stress in cancer.
PUBDATE: 19950101
DNA of cancers such as renal cell carcinoma and mammary invasive ductal carcinoma, is persistently exposed to more oxidative stress than that of adjacent normal tissue. We suggest that the concept of 'persistent oxidative stress in cancer' may open up a new research area, explaining part of the characteristic tumor biology of cancer such as activated transcription factors and proto-oncogenes, genomic instability, chemotherapy-resistance, invasion and metastasis.

11. DOCID:23775 SCORE: 0.00373613188703648
DOCNO: 7808686
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secondary
QUALIFIER: secondary
QUALIFIER: complications
QUALIFIER: secondary
QUALIFIER: pathology
QUALIFIER: etiology
AUTHOR: V Bruzzese V
AUTHOR: F Biferali F
AUTHOR: S Paventi S
AFFILIATION: Divisione Medicina Generale, Ospedale S. Giacomo in Augusta, Roma.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Minerva medica.
COUNTRY: ITALY
TITLE: [Neoplastic pericarditis secondary to ovarian adenocarcinoma. Report of a clinical case]
PUBDATE: 19941101
The pericardial metastatic disease is rare in genital cancers but is frequent in all other cancer. The authors report the case of a female affected by both papillary ovarian cancer and pericardial metastatic disease. Carcinomatous pericarditis began with cardiac tamponade. This pericarditis is very rare during ovarian cancer and there is little informations in the literature about it. The clinical picture showed an acuteness that cleared up with many pericardial tapping paracenteses, and after six cycles of polychemotherapy we obtained the disappearance of pericardial effusion and metastasis with total disappearance of abdominal metastases and the total remission of the cancer.

12. DOCID:27979 SCORE: 0.00371945336633542
DOCNO: 11357148
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
AUTHOR: J Peto J
AFFILIATION: Institute of Cancer Research, Sutton, Surrey SM2 5NG, and London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nature.
COUNTRY: England
TITLE: Cancer epidemiology in the last century and the next decade.
PUBDATE: 20010501
By the early 1980s, epidemiologists had identified many important causes of cancer. They had also proposed the 'multi-stage' model of cancer, although none of the hypothesized events in human carcinogenesis had then been identified. The remarkable advances in cell and molecular biology over the past two decades have transformed the scope and methods of cancer epidemiology. There have been a few new discoveries based purely on traditional methods, and many long-suspected minor risks have been estimated more precisely. But modern epidemiological studies often depend on genetic, biochemical or viral assays that had not been developed 20 years ago.

13. DOCID:23400 SCORE: 0.00370394741394787
DOCNO: 9179488
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
QUALIFIER: radiation effects
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
AUTHOR: C MacLeod C
AUTHOR: E Moylan E
AUTHOR: G L Falk GL
AFFILIATION: Department of Radiation Oncology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E.
COUNTRY: SCOTLAND
TITLE: Carcinoma of the esophagus treated with radical chemoradiation 19 years after irradiation for recurrent breast cancer.
PUBDATE: 19970401
Prior irradiation to a site is a relative and often absolute contraindication to further irradiation because the tolerance dose of normal tissues is usually exceeded and therefore the risk of serious long-term side-effects is high. This case report describes radical salvage chemoradiation for an esophageal carcinoma in a patient who had prior high-dose neck and chest wall irradiation for the management of a breast cancer 19 years previously.

14. DOCID:27133 SCORE: 0.00366672228581337
DOCNO: 11383248
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Orchiectomy
DESCRIPTOR: Prostatectomy
QUALIFIER: psychology
QUALIFIER: surgery
AUTHOR: P S Marschke PS
AFFILIATION: Department of Urology, Johns Hopkins School of Medicine, JHOC-4th Floor Urology, 601 N Caroline St, Baltimore, MD 21287-0850, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in oncology nursing.
COUNTRY: United States
TITLE: The role of surgery in the treatment of prostate cancer.
PUBDATE: 20010501
OBJECTIVES: To describe the role of surgery in the treatment of organ-confined prostate cancer and advanced prostate cancer. DATA SOURCES: Journals, textbooks, and personal communication. CONCLUSIONS: Radical prostatectomy plays a possible role in curing those patients with disease confined to the prostate. Bilateral orchiectomy plays a palliative role for patients with advanced disease. IMPLICATIONS FOR NURSING PRACTICE: This article provides nurses with the knowledge needed to teach patients about how the surgery is performed, the associated complications, and the likelihood of cancer control.