0. DOCID:19801 SCORE: 0.00583465533009774
DOCNO: 1561266
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mammaplasty
QUALIFIER: radiotherapy
AUTHOR: N Handel N
AUTHOR: B Lewinsky B
AUTHOR: J R Waisman JR
AFFILIATION: Breast Center, Van Nuys, Calif. 91405.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Plastic and reconstructive surgery.
COUNTRY: UNITED STATES
TITLE: Reduction mammaplasty following radiation therapy for breast cancer.
PUBDATE: 19920501
This report describes an unusual case in which reduction mammaplasty was performed following radiation therapy for breast cancer. While healing was significantly prolonged (compared with the nonirradiated contralateral breast), the final result was satisfactory from both the functional and the aesthetic standpoint. Women with prior radiation therapy may be considered candidates for reduction mammaplasty. Patients should be warned of the increased risks of wound complications, the likelihood of delayed healing, and the possibility of pigmentation changes in the grafted nipple-areola complex. We elected to transpose the nipple as a full-thickness graft, but consideration also might be given to use of an inferiorly based pedicle flap.

1. DOCID:22913 SCORE: 0.00422217551554887
DOCNO: 7578386
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: methods
AUTHOR: P Rossi P
AUTHOR: M Bezzi M
AFFILIATION: Department of Radiology, University of Rome La Sapienza, Policlinico Umberto I, Italy.
PUBTYPE: Journal Article
JOURNALTITLE: Current opinion in oncology.
COUNTRY: UNITED STATES
TITLE: Interventional radiology in gastrointestinal neoplasms.
PUBDATE: 19950701
Interventional radiology plays a significant role in different fields of gastrointestinal oncology. Percutaneous techniques can be used to diagnose and stage bile duct and pancreatic cancer. Palliation of esophageal tumors and malignant biliary obstruction may be achieved with interventional techniques, whereas curative attempts are directed mainly towards primary and secondary liver tumors. The therapeutic potential of interventional radiology is still expanding, as are all other forms of minimally invasive therapy. This article reviews the relevant contributions on this subject that have appeared in the past year. The introduction of new techniques is described, and the results of clinical studies are discussed.

2. DOCID:22740 SCORE: 0.00399348359808298
DOCNO: 7742518
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Laparoscopy
QUALIFIER: surgery
AUTHOR: J M Childers JM
AUTHOR: A Nasseri A
AFFILIATION: Department of Obstetrics and Gynecology, University of Arizona, Tucson, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in obstetrics & gynecology.
COUNTRY: UNITED STATES
TITLE: Minimal access surgery in gynecologic cancer: we can, but should we?
PUBDATE: 19950201
Operative laparoscopists continue to refine surgical techniques applicable to patients with gynecologic malignancies. Various techniques for radical hysterectomy and larger series of patients with endometrial cancer have now been reported. The technical feasibility of such operations is being established. Although oncologic patients may enjoy the known benefits of laparoscopic surgery, such as shorter hospitalization, the known shortcomings, such as longer operative times and increased cost, are a concern. The unknown shortcomings and the unknown overall survival of laparoscopically managed patients continue to keep the majority of oncologic surgeons a safe distance away.

3. DOCID:20969 SCORE: 0.00390577742812919
DOCNO: 7821417
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Oxidative Stress
QUALIFIER: metabolism
QUALIFIER: metabolism
AUTHOR: S Toyokuni S
AUTHOR: K Okamoto K
AUTHOR: J Yodoi J
AUTHOR: H Hiai H
AFFILIATION: Department of Pathology, Faculty of Medicine, Kyoto University, Japan.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: FEBS letters.
COUNTRY: NETHERLANDS
TITLE: Persistent oxidative stress in cancer.
PUBDATE: 19950101
DNA of cancers such as renal cell carcinoma and mammary invasive ductal carcinoma, is persistently exposed to more oxidative stress than that of adjacent normal tissue. We suggest that the concept of 'persistent oxidative stress in cancer' may open up a new research area, explaining part of the characteristic tumor biology of cancer such as activated transcription factors and proto-oncogenes, genomic instability, chemotherapy-resistance, invasion and metastasis.

4. DOCID:23775 SCORE: 0.00373613188703648
DOCNO: 7808686
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secondary
QUALIFIER: secondary
QUALIFIER: complications
QUALIFIER: secondary
QUALIFIER: pathology
QUALIFIER: etiology
AUTHOR: V Bruzzese V
AUTHOR: F Biferali F
AUTHOR: S Paventi S
AFFILIATION: Divisione Medicina Generale, Ospedale S. Giacomo in Augusta, Roma.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Minerva medica.
COUNTRY: ITALY
TITLE: [Neoplastic pericarditis secondary to ovarian adenocarcinoma. Report of a clinical case]
PUBDATE: 19941101
The pericardial metastatic disease is rare in genital cancers but is frequent in all other cancer. The authors report the case of a female affected by both papillary ovarian cancer and pericardial metastatic disease. Carcinomatous pericarditis began with cardiac tamponade. This pericarditis is very rare during ovarian cancer and there is little informations in the literature about it. The clinical picture showed an acuteness that cleared up with many pericardial tapping paracenteses, and after six cycles of polychemotherapy we obtained the disappearance of pericardial effusion and metastasis with total disappearance of abdominal metastases and the total remission of the cancer.

5. DOCID:23400 SCORE: 0.00370394741394787
DOCNO: 9179488
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
QUALIFIER: radiation effects
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
AUTHOR: C MacLeod C
AUTHOR: E Moylan E
AUTHOR: G L Falk GL
AFFILIATION: Department of Radiation Oncology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E.
COUNTRY: SCOTLAND
TITLE: Carcinoma of the esophagus treated with radical chemoradiation 19 years after irradiation for recurrent breast cancer.
PUBDATE: 19970401
Prior irradiation to a site is a relative and often absolute contraindication to further irradiation because the tolerance dose of normal tissues is usually exceeded and therefore the risk of serious long-term side-effects is high. This case report describes radical salvage chemoradiation for an esophageal carcinoma in a patient who had prior high-dose neck and chest wall irradiation for the management of a breast cancer 19 years previously.

6. DOCID:21569 SCORE: 0.00348185811444069
DOCNO: 7780111
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: biosynthesis
QUALIFIER: drug effects
QUALIFIER: pharmacology
AUTHOR: X Chen X
AUTHOR: R Han R
AFFILIATION: Department of Pharmacology, Institute of Materia Medica, CAMS, Beijing.
PUBTYPE: Journal Article
JOURNALTITLE: Chinese medical sciences journal = Chung-kuo i hsüeh k'o hsüeh tsa chih / Chinese Academy of Medical Sciences.
COUNTRY: CHINA
TITLE: Effect of glycyrrhetinic acid on DNA damage and unscheduled DNA synthesis induced by benzo(a)pyrene.
PUBDATE: 19950301
Glycyrrhetinic acid (GA) is an active component of Glycyrrhiza uraleusis fisch. In this study, GA was found to inhibit ear edema and ornithine decarboxylase (ODC) activity induced by croton oil in mice. GA could also protect rapid DNA damage and decrease the unscheduled DNA synthesis induced by benzo(a)pyrene. The results demonstrate that GA has a potential cancer chemopreventive activity.

7. DOCID:17273 SCORE: 0.00346216414357179
DOCNO: 1344668
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: pathogenicity
AUTHOR: J V Solnick JV
AUTHOR: L S Tompkins LS
AFFILIATION: Department of Medicine, Stanford University School of Medicine, California 94305.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Infectious agents and disease.
COUNTRY: UNITED STATES
TITLE: Helicobacter pylori and gastroduodenal disease: pathogenesis and host-parasite interaction.
PUBDATE: 19921201
Helicobacter pylori has been shown to be the cause of chronic active gastritis and the evidence that it is involved in the development of peptic ulcer disease and gastric cancer is compelling. Narrow host range, tissue specificity, and chronic inflammation are hallmarks of infection. The study of virulence determinants has just begun but it seems likely that urease, adhesins, cytotoxins, and mediators of inflammation will prove to be important.

8. DOCID:22906 SCORE: 0.00338884433113843
DOCNO: 8634979
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Health Care Costs
QUALIFIER: economics
AUTHOR: J S Bailes JS
AFFILIATION: American Society of Clinical Oncology, Alexandria, Virginia 22314, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: The economics of cancer care.
PUBDATE: 19951101
Considerable attention has been paid to the high cost of cancer care. These medical services are expensive, accounting for 10% of total health care expenditures. Factors contributing to high costs include (1) the likelihood that anticancer treatments will lead to costly medical complications: (2) intensive research and development necessary to ensure rapid introduction of a broad array of treatment options; and (3) specialized facilities required for delivery of care. Such efforts as rationing of care and utilizing practice guidelines have been ineffective in controlling costs. To realize savings, we must develop new therapies with sufficient specificity so that anticancer interventions do not impair the patient's general health.

9. DOCID:19018 SCORE: 0.00330100897830613
DOCNO: 8464136
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Genetic Counseling
DESCRIPTOR: Human Genome Project
QUALIFIER: genetics
AUTHOR: D L Breo DL
PUBTYPE: Journal Article
JOURNALTITLE: JAMA : the journal of the American Medical Association.
COUNTRY: UNITED STATES
TITLE: Altered fates--counseling families with inherited breast cancer.
PUBDATE: 19930401
Breo profiles Barbara Weber, M.D., and Francis Collins, M.D., of the University of Michigan School of Medicine's breast cancer clinic, and their work isolating and identifying genetic markers for the gene that means an 85% lifetime risk of developing breast cancer, as well as a significantly higher risk of ovarian cancer. Their discovery is expected to revolutionize women's health care and to present society with daunting economic, ethical, and counseling issues. [Collins discovered the genes that cause cystic fibrosis, neurofibromatosis, and Huntington's disease. He was named director of the National Center for Human Genome Research at the National Institutes of Health in April 1993].

10. DOCID:17407 SCORE: 0.00323850996723124
DOCNO: 1463995
AUTHOR: F De Waard F
AFFILIATION: Department of Epidemiology, University of Utrecht, The Netherlands.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP).
COUNTRY: ENGLAND
TITLE: Preventive intervention in breast cancer, but when?
PUBDATE: 19921001
After an introductory note on primary preventive intervention of breast cancer during adulthood, the author defends and extends a hypothesis that relates most of the known risk factors for this disease to the development of preneoplastic lesions in the breast. If changes in lifestyle concerning nutritional and/or reproductive risk factors during puberty and adolescence would turn out to be unacceptable socially, an alternative approach might be found in chemoprevention based on cell differentiation.

11. DOCID:21554 SCORE: 0.00309344953295806
DOCNO: 8865481
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
AUTHOR: B A Lowe BA
AFFILIATION: Division of Urology, Oregon Health Sciences University, Portland 97201, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in urologic oncology.
COUNTRY: UNITED STATES
TITLE: Management of stage T1a prostate cancer.
PUBDATE: 19960801
The patient with incidentally discovered prostate cancer by transurethral resection of the prostate (TURP) presents a difficult management problem for the clinician. These tumors are small and generally of low biologic potential. Offering aggressive treatment is not necessary in most patients; though in some patients, the tumor is not organ confined. Selecting that patient who may require tumor eradication to optimize survival requires careful analysis of known histological parameters identified at the time of diagnosis, an estimation of projected individual survival, and extensive counseling regarding options.

12. DOCID:23922 SCORE: 0.00301875124073837
DOCNO: 9059411
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Magnetic Resonance Imaging
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: S Mussurakis S
AUTHOR: P J Carleton PJ
AUTHOR: L W Turnbull LW
AFFILIATION: Centre for MR Investigations, University of Hull, Hull Royal Infirmary, United Kingdom.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Acta radiologica (Stockholm, Sweden : 1987)
COUNTRY: DENMARK
TITLE: MR imaging of primary non-Hodgkin's breast lymphoma. A case report.
PUBDATE: 19970101
In this report we describe the MR imaging findings, including dynamic data, in a patient with primary non-Hodgkin's lymphoma of the breast. The precontrast T1-weighted sequence showed several hypointense, ill-defined, non-spiculated masses. In the T2-weighted images the masses showed a hyperintense halo. In the dynamic and postcontrast sequences all lesions enhanced markedly, and a further large mass was discovered. In comparison to mammography and sonography, only MR imaging identified the multicentric extent of the tumour. Differentiation from invasive cancer, based on either MR or conventional imaging features, was not possible.

13. DOCID:17920 SCORE: 0.00300731137535204
DOCNO: 8237741
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Carcinoma, Basal Cell
DESCRIPTOR: Skin Neoplasms
AUTHOR: A S Kuflik AS
AUTHOR: C K Janniger CK
AFFILIATION: North Shore University Hospital, Manhasset, New York.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: American family physician.
COUNTRY: UNITED STATES
TITLE: Basal cell carcinoma.
PUBDATE: 19931101
Fair-skinned persons who have had significant exposure to the sun are at greatest risk for basal cell carcinoma. Clinically, basal cell carcinomas include numerous nodular and flat types. The lesions of basal cell carcinoma are usually asymptomatic until enlargement, bleeding or invasion of underlying tissue occurs. Metastasis is rare. A biopsy should be obtained before destructive treatment is carried out. Surgical excision, curettage and electrodesiccation or cryosurgery are acceptable procedures for removal of most lesions. Periodic follow-up is necessary to screen for new or recurrent skin cancer.

14. DOCID:19268 SCORE: 0.00298116076214345
DOCNO: 2381055
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
AUTHOR: K Izumiyama K
AUTHOR: Y Imajo Y
AUTHOR: J Hiratsuka J
AUTHOR: S Nishishita S
AUTHOR: Y Furukawa Y
AUTHOR: M Suzuki M
AUTHOR: H Tanaka H
AFFILIATION: Dept. of Radiation Oncology, Kawasaki Medical School.
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Radiotherapy of prostatic cancer]
PUBDATE: 19900801
From 1976 to 1988, 33 patients with a prostatic cancer were treated with radiotherapy at Kawasaki Medical School. The age of these patients ranged from 45 to 82 with the average being 69 years. The actuarial 5 year survival rates for patients in stages B (n = 6), C (n = 12), D1 (n = 5), or D2 (n = 10) were 100%, 65%, 50%, and 40%, respectively. The for those with an adenocarcinoma that was well differentiated (n = 5), moderately differentiated (n = 13), or poorly differentiated (n = 15) was (were?) 100%, 58%, and 41%, respectively.