0. DOCID:30774 SCORE: 0.00499344580281483
DOCNO: 11890096
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: genetics
QUALIFIER: genetics
QUALIFIER: drug therapy
QUALIFIER: genetics
AUTHOR: Tetsuya Mitsudomi T
AFFILIATION: Department of Thoracic Surgery, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya 464-8681, Japan. mitsudom@leo.bekkoame.ne.jp
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: Japan
TITLE: Molecular lesions as targets for diagnosis and therapy of lung cancer.
PUBDATE: 20020201
Alteration of the p53 tumor suppressor gene is one of the most frequently seen molecular lesions in human lung cancer. It is of importance to integrate translational science into clinical practice. In our laboratory, we are in search for clinical utility of p53 gene alterations in management of patients with lung cancer. Here, we would like to discuss p53 alterations as a prognostic factor for lung cancer patients or as a predictor of chemosensitivity.

1. DOCID:30185 SCORE: 0.00499344441803905
DOCNO: 14612484
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: history
AUTHOR: Marcia L Meldrum ML
AFFILIATION: Department of History, University of California-Los Angeles, Los Angeles 90095-1473, USA. mlynnmel@earthlink.net
PUBTYPE: Historical Article
PUBTYPE: Journal Article
JOURNALTITLE: JAMA : the journal of the American Medical Association.
COUNTRY: United States
TITLE: A capsule history of pain management.
PUBDATE: 20031101
Pain is a complex clinical problem. Assessment depends on verbal report, and the patient's physical perceptions may be modified by cognitive and affective factors. The salience of pain as a problem in its own right has grown since 1945 and new therapeutic alternatives have developed from research and from new theoretical perspectives. This short historical review of the highlights of the history of pain management gives particular emphasis to the 20th century and to chronic and cancer pain.

2. DOCID:13339 SCORE: 0.00385975722883819
DOCNO: 3696750
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Infusion Pumps
QUALIFIER: instrumentation
QUALIFIER: administration & dosage
QUALIFIER: administration & dosage
QUALIFIER: administration & dosage
QUALIFIER: physiopathology
QUALIFIER: drug therapy
AUTHOR: F I Ahlgren FI
AUTHOR: M B Ahlgren MB
AFFILIATION: Department of Anaesthesiology, General Hospital, Malmö, Sweden.
PUBTYPE: Journal Article
JOURNALTITLE: Pain.
COUNTRY: NETHERLANDS
TITLE: Epidural administration of opiates by a new device.
PUBDATE: 19871201
Epidural administration of opiates as a long-term treatment of cancer pain, even for out-patients, is now well established. Most reports describe intermittent injections given several times a day, which may have technical and personal disadvantages. Continuous epidural infusion may be preferable. This report describes 16 patients who were treated with epidural opiates delivered by plastic infusion pumps. Pain relief was effective, the equipment was inexpensive and home treatment was easily accomplished.

3. DOCID:30402 SCORE: 0.00354833038604926
DOCNO: 14520433
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Bone Marrow Transplantation
DESCRIPTOR: Hematopoietic Stem Cell Transplantation
QUALIFIER: adverse effects
QUALIFIER: chemically induced
QUALIFIER: therapy
AUTHOR: C Palmieri C
AUTHOR: R Gillmore R
AUTHOR: A Menzies-Gow A
AUTHOR: S Fishpool S
AUTHOR: D Robinson D
AUTHOR: R Shaw R
AUTHOR: R C Coombes RC
AFFILIATION: Department of Medical Oncology, Charing Cross Hospital, Fulham Palace Road, London, UK. c.palmieri@ic.ac.uk
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Bone marrow transplantation.
COUNTRY: England
TITLE: Resolution of late-onset asthma following high-dose chemotherapy.
PUBDATE: 20031001
We describe a patient with moderately severe (British Thorax Society Step IV/V) asthma requiring regular inhaled and oral corticosteroids to control symptoms who experienced resolution of her asthma following high-dose chemotherapy and autologous stem cell transplantation for breast cancer. As far as the authors are aware this is the first reported case.

4. DOCID:3649 SCORE: 0.00319464924258222
DOCNO: 163141
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiography
AUTHOR: H Grossman H
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: The evaluation of abdominal masses in children with emphasis on noninvasive methods. A roentgenographic approach.
PUBDATE: 19750301
Intravenous urography with total body opacification, and tomography as required, often give the most information toward evaluating abdominal masses in children. Ultrasonography is a noninvasive procedure which defines normal structures and differentiates cystic and solid tumors. The combination of these studies gives sufficient information about renal tumors to plan for possible surgery. Arteriography is not necessary for the diagnosis of Wilms' tumor, nor its surgical or medical management. Pseudotumor of the kidney is due to focal cortical hyperplasia. It can be diagnosed by nephrotomography, renal arteriography or renal scanning. The latter method is most accurate and has the lowest morbidity. Aortography is advisable in the evaluation of a patient with pheochromocytoma in an attempt to locate multiple tumors. Determining the extent of abdominal neuroblastoma by angiography and lymphangiography does not appear to influence the mode of therapy, not the survival rate; therefore, invasive diagnostic procedures do not appear to be indicated in neuroblastoma. Angiography is necessary in the evaluation of liver cancer. If one lobe is determined to be free of disease, lobectomy is a possible cure. Splenic cysts and choledochal cysts can be diagnosed by noninvasive methods such as ultrasonography or radioisotope scanning. Arteriography and percutaneous opacification are not necessary to make these diagnoses.

5. DOCID:23959 SCORE: 0.00315438316465281
DOCNO: 7600136
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Helicobacter pylori
QUALIFIER: etiology
QUALIFIER: complications
QUALIFIER: etiology
QUALIFIER: etiology
AUTHOR: S Eidt S
AUTHOR: M Stolte M
AFFILIATION: Institute of Pathology, University of Cologne, Germany.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: European journal of gastroenterology & hepatology.
COUNTRY: ENGLAND
TITLE: The significance of Helicobacter pylori in relation to gastric cancer and lymphoma.
PUBDATE: 19950401
The evidence linking Helicobacter pylori and non-cardia gastric adenocarcinoma is accumulating. Patterns of strain specificities and host factors that increase epithelial proliferation and have implications for mutagenic effects are evolving. The decision by the World Health Organization and the International Agency for Research on Cancer to classify H. pylori as a 'definite' carcinogen, however, represents a milestone in the association of H. pylori with gastric carcinogenesis. The importance of H. pylori in gastric lymphoma has been underscored by the finding that H. pylori eradication can induce complete regression in low-grade mucosa-associated lymphoid tissue lymphomas, at least in the early stages of development.

6. DOCID:5317 SCORE: 0.00304643277021827
DOCNO: 6174068
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
AUTHOR: B Windeyer B
PUBTYPE: Journal Article
JOURNALTITLE: Annals of the Academy of Medicine, Singapore.
COUNTRY: SINGAPORE
TITLE: Therapeutic radiology -- a review.
PUBDATE: 19810701
Radiotherapy has played an important role in the curative and palliative treatment of cancer and should continue to do so in the future. As the radiotherapist is concerned with the overall management of the cancer patient, he should be a well trained clinician. Notable advances and improvements in apparatus have taken place recently. Better treatment planning, new forms of after loading techniques, neutron therapy, hyperthermia and other interesting developments are also discussed. With these advances, problems of radiological protection are reviewed and recommendations made from time to time by the International Commission and Radiological Protection to ensure the safety of both staff and patients.

7. DOCID:20250 SCORE: 0.00278987709114149
DOCNO: 8862710
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Taxoids
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: analogs & derivatives
AUTHOR: J P Armand JP
AFFILIATION: Department of Medicine, Institut Gustave-Roussy, Villejuif, Paris, France.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Anti-cancer drugs.
COUNTRY: ENGLAND
TITLE: The clinical rationale for developing docetaxel (Taxotere).
PUBDATE: 19960801
Clinical empiricism has recognized resistant breast cancer as a privileged target for docetaxel (Taxotere). This worldwide registration will offer medical oncologists the opportunity to develop new indications for docetaxel. Pharmacokinetics, preclinical optimal combination and clinical practice will constitute the rationale for the future development of docetaxel.

8. DOCID:1939 SCORE: 0.00269856415583485
DOCNO: 324083
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
AUTHOR: D Zoedler D
AUTHOR: G Limbacher G
PUBTYPE: Journal Article
JOURNALTITLE: Der Urologe. Ausg. A.
COUNTRY: GERMANY, WEST
TITLE: [Report of 100 total prostatectomies (author's transl)]
PUBDATE: 19770301
A total retropubic prostatectomy is an exact, clearly defined operation, which, in our hands, has been extensively standardized: it lasts an average of 1 1/2 h, results in relatively little blood loss-in only 20% of the cases is one or more units of whole blood utilized-and is accompanied by complications that are kept within tolerable boundaries. Complete enuresis can be avoided by using a particular stitching technique for the outlet of the bladder. A considerable incontinence occurred in only one patient, who during the day was temporarily forced to wear a Cunningham clamp. In the postoperative stationary phase, mortality was 2%. A radical prostatectomy makes complete recovery from cancer of the prostate possible without mutilation and without aggravating functional injuries. It has, therefore, a secure place in the surgical therapy of cancer.

9. DOCID:30278 SCORE: 0.002651528310941
DOCNO: 14763146
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: metabolism
QUALIFIER: metabolism
QUALIFIER: metabolism
QUALIFIER: metabolism
AUTHOR: Jacques Bosq J
AUTHOR: Frédérique Penault-Llorca F
AUTHOR: Jean-Claude Sabourin JC
AFFILIATION: Département de pathologie, Institut Gustave-Roussy, rue Camille-Desmoulins, 94805 Villejuif. bosq@igr.fr
PUBTYPE: Journal Article
JOURNALTITLE: Bulletin du cancer.
COUNTRY: France
TITLE: [Expression of epidermal growth factor receptor and its ligands in other malignant tumor pathologies]
PUBDATE: 20031101
The aim of this review was to describe expression of epithelial growth factor receptor (EGFR) and of its ligands in a panel of tumours (which are not specified elsewhere in this special issue of Bulletin du Cancer): squamous cell carcinomas, adenocarcinomas, sarcomas, brain and germ line tumours. The role of EGFR and its ligands in the carcinogenesis and the progression of these tumours, as well as the relevance of targeting EGFR.

10. DOCID:22643 SCORE: 0.00262309324165023
DOCNO: 8965365
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: K Sugino K
AUTHOR: K Ito K
AFFILIATION: Ito Hospital.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nippon rinsho. Japanese journal of clinical medicine.
COUNTRY: JAPAN
TITLE: [Thyroid microcarcinoma]
PUBDATE: 19960501
The term "early cancer of the thyroid" is not clearly defined. Recently, microcarcinoma of the thyroid, less than 10 mm, has been frequently detected and in Ito Hospital smaller papillary carcinoma has increased in these 10 years. As rate of microcarcinoma found in autopsy cases were reported 10-28.4% in Japan, all of thyroid microcarcinoma are not thought to be developed clinically. In our hospital, papillary microcarcinoma diagnosed preoperatively underwent lobectomy with modified neck dissection in principle. Lymph node metastases were found in 65% of patients with papillary microcarcinoma. Further studies and discussion concerned whether thyroid microcarcinoma should be treated and how it should be treated, is necessary.

11. DOCID:25737 SCORE: 0.00258194996596751
DOCNO: 11176226
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Education, Medical, Graduate
QUALIFIER: surgery
AUTHOR: J W Orr JW
AUTHOR: P Y Roland PY
AUTHOR: P J Orr PJ
AUTHOR: D D Bolen DD
AUTHOR: S L Hutcheson SL
AFFILIATION: Gynecologic Oncology and Gynecologic Cancer Research, Lee Cancer Care, Lee Memorial Hospital, Fort Myers, Florida 33901, USA. James.Orr@LeeMemorial.ORG
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in obstetrics & gynecology.
COUNTRY: England
TITLE: Subspecialty training: does it affect the outcome of women treated for a gynecologic malignancy?
PUBDATE: 20010201
A review of available direct and indirect scientific reports strongly suggests that subspecialty training increases the likelihood that the appropriate surgical procedure will be completed in women operated on for gynecologic cancer. It is likely that specialty care lessens the costs associated with diagnosis, treatment and surveillance, and frequently improves survival.

12. DOCID:27196 SCORE: 0.00256187905603389
DOCNO: 10580865
AUTHOR: A W Lee AW
AUTHOR: W M Sze WM
AUTHOR: J F Fowler JF
AUTHOR: R Chappell R
AUTHOR: S F Leung SF
AUTHOR: P Teo P
AFFILIATION: Department of Clinical Oncology, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong, People's Republic of China.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
COUNTRY: IRELAND
TITLE: Caution on the use of altered fractionation for nasopharyngeal carcinoma.
PUBDATE: 19990901
Randomized trials and overviews on the value of altered fractionation for head and neck cancers are reviewed. Attention is drawn to the unexpectedly high incidence of temporal lobe necrosis incurred in patients with nasopharyngeal carcinoma. Preliminary analyses suggest that incomplete repair is likely to be the major factor, even a 6-h interfraction interval may be inadequate if substantial volumes of nervous tissues are included within the target volume.

13. DOCID:22465 SCORE: 0.00254923375704502
DOCNO: 9457985
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: methods
QUALIFIER: surgery
QUALIFIER: adverse effects
QUALIFIER: chemically induced
QUALIFIER: therapy
AUTHOR: T Römer T
AFFILIATION: Department of Obstetrics and Gynecology, Ernst-Moritz-Arndt-University of Greifswald, Germany.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.
COUNTRY: IRELAND
TITLE: Successful treatment of recurrent uterine bleeding during tamoxifen therapy by endometrial ablation.
PUBDATE: 19950401
Recurrent bleeding occurred in a premenopausal breast cancer woman during tamoxifen therapy. This bleeding required three curettages. Atypical hyperplasia and carcinoma were excluded, and the patient was prepared for endometrial ablation with two GnRH agonist injections. An endometrial ablation using the roller ball technique was carried out without complications. Tamoxifen therapy was continued postoperatively. During 24 months' follow-up the patient experienced no bleeding and no endometrium was seen by sonography.

14. DOCID:29998 SCORE: 0.00251641208437825
DOCNO: 12879794
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
QUALIFIER: etiology
QUALIFIER: epidemiology
QUALIFIER: etiology
AUTHOR: Annie Sasco A
AFFILIATION: Centre international de recherche sur le cancer Unité d'épidémiologie pour la prévention du cancer et Institut national de la santé et de la recherche médicale 69372 Lyon. sasco@iarc.fr
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: La Revue du praticien.
COUNTRY: France
TITLE: [Epidemiology of lung carcinoma]
PUBDATE: 20030401
Lung cancer is the most common cancer in the world, either in terms of incidence or mortality, and it is still increasing in particular in the developing world and among women. The vast majority of lung cancers are due to tobacco smoking and therefore primary prevention through efficient tobacco control is possible. Occupational carcinogens are also recognised and the role of environmental exposures remains to be defined.