0. DOCID:30774 SCORE: 0.00499344580281483
DOCNO: 11890096
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: genetics
QUALIFIER: genetics
QUALIFIER: drug therapy
QUALIFIER: genetics
AUTHOR: Tetsuya Mitsudomi T
AFFILIATION: Department of Thoracic Surgery, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya 464-8681, Japan. mitsudom@leo.bekkoame.ne.jp
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: Japan
TITLE: Molecular lesions as targets for diagnosis and therapy of lung cancer.
PUBDATE: 20020201
Alteration of the p53 tumor suppressor gene is one of the most frequently seen molecular lesions in human lung cancer. It is of importance to integrate translational science into clinical practice. In our laboratory, we are in search for clinical utility of p53 gene alterations in management of patients with lung cancer. Here, we would like to discuss p53 alterations as a prognostic factor for lung cancer patients or as a predictor of chemosensitivity.

1. DOCID:30185 SCORE: 0.00499344441803905
DOCNO: 14612484
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: history
AUTHOR: Marcia L Meldrum ML
AFFILIATION: Department of History, University of California-Los Angeles, Los Angeles 90095-1473, USA. mlynnmel@earthlink.net
PUBTYPE: Historical Article
PUBTYPE: Journal Article
JOURNALTITLE: JAMA : the journal of the American Medical Association.
COUNTRY: United States
TITLE: A capsule history of pain management.
PUBDATE: 20031101
Pain is a complex clinical problem. Assessment depends on verbal report, and the patient's physical perceptions may be modified by cognitive and affective factors. The salience of pain as a problem in its own right has grown since 1945 and new therapeutic alternatives have developed from research and from new theoretical perspectives. This short historical review of the highlights of the history of pain management gives particular emphasis to the 20th century and to chronic and cancer pain.

2. DOCID:30402 SCORE: 0.00354833038604926
DOCNO: 14520433
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Bone Marrow Transplantation
DESCRIPTOR: Hematopoietic Stem Cell Transplantation
QUALIFIER: adverse effects
QUALIFIER: chemically induced
QUALIFIER: therapy
AUTHOR: C Palmieri C
AUTHOR: R Gillmore R
AUTHOR: A Menzies-Gow A
AUTHOR: S Fishpool S
AUTHOR: D Robinson D
AUTHOR: R Shaw R
AUTHOR: R C Coombes RC
AFFILIATION: Department of Medical Oncology, Charing Cross Hospital, Fulham Palace Road, London, UK. c.palmieri@ic.ac.uk
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Bone marrow transplantation.
COUNTRY: England
TITLE: Resolution of late-onset asthma following high-dose chemotherapy.
PUBDATE: 20031001
We describe a patient with moderately severe (British Thorax Society Step IV/V) asthma requiring regular inhaled and oral corticosteroids to control symptoms who experienced resolution of her asthma following high-dose chemotherapy and autologous stem cell transplantation for breast cancer. As far as the authors are aware this is the first reported case.

3. DOCID:30278 SCORE: 0.002651528310941
DOCNO: 14763146
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: metabolism
QUALIFIER: metabolism
QUALIFIER: metabolism
QUALIFIER: metabolism
AUTHOR: Jacques Bosq J
AUTHOR: Frédérique Penault-Llorca F
AUTHOR: Jean-Claude Sabourin JC
AFFILIATION: Département de pathologie, Institut Gustave-Roussy, rue Camille-Desmoulins, 94805 Villejuif. bosq@igr.fr
PUBTYPE: Journal Article
JOURNALTITLE: Bulletin du cancer.
COUNTRY: France
TITLE: [Expression of epidermal growth factor receptor and its ligands in other malignant tumor pathologies]
PUBDATE: 20031101
The aim of this review was to describe expression of epithelial growth factor receptor (EGFR) and of its ligands in a panel of tumours (which are not specified elsewhere in this special issue of Bulletin du Cancer): squamous cell carcinomas, adenocarcinomas, sarcomas, brain and germ line tumours. The role of EGFR and its ligands in the carcinogenesis and the progression of these tumours, as well as the relevance of targeting EGFR.

4. DOCID:25737 SCORE: 0.00258194996596751
DOCNO: 11176226
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Education, Medical, Graduate
QUALIFIER: surgery
AUTHOR: J W Orr JW
AUTHOR: P Y Roland PY
AUTHOR: P J Orr PJ
AUTHOR: D D Bolen DD
AUTHOR: S L Hutcheson SL
AFFILIATION: Gynecologic Oncology and Gynecologic Cancer Research, Lee Cancer Care, Lee Memorial Hospital, Fort Myers, Florida 33901, USA. James.Orr@LeeMemorial.ORG
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in obstetrics & gynecology.
COUNTRY: England
TITLE: Subspecialty training: does it affect the outcome of women treated for a gynecologic malignancy?
PUBDATE: 20010201
A review of available direct and indirect scientific reports strongly suggests that subspecialty training increases the likelihood that the appropriate surgical procedure will be completed in women operated on for gynecologic cancer. It is likely that specialty care lessens the costs associated with diagnosis, treatment and surveillance, and frequently improves survival.

5. DOCID:27196 SCORE: 0.00256187905603389
DOCNO: 10580865
AUTHOR: A W Lee AW
AUTHOR: W M Sze WM
AUTHOR: J F Fowler JF
AUTHOR: R Chappell R
AUTHOR: S F Leung SF
AUTHOR: P Teo P
AFFILIATION: Department of Clinical Oncology, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong, People's Republic of China.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
COUNTRY: IRELAND
TITLE: Caution on the use of altered fractionation for nasopharyngeal carcinoma.
PUBDATE: 19990901
Randomized trials and overviews on the value of altered fractionation for head and neck cancers are reviewed. Attention is drawn to the unexpectedly high incidence of temporal lobe necrosis incurred in patients with nasopharyngeal carcinoma. Preliminary analyses suggest that incomplete repair is likely to be the major factor, even a 6-h interfraction interval may be inadequate if substantial volumes of nervous tissues are included within the target volume.

6. DOCID:29998 SCORE: 0.00251641208437825
DOCNO: 12879794
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
QUALIFIER: etiology
QUALIFIER: epidemiology
QUALIFIER: etiology
AUTHOR: Annie Sasco A
AFFILIATION: Centre international de recherche sur le cancer Unité d'épidémiologie pour la prévention du cancer et Institut national de la santé et de la recherche médicale 69372 Lyon. sasco@iarc.fr
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: La Revue du praticien.
COUNTRY: France
TITLE: [Epidemiology of lung carcinoma]
PUBDATE: 20030401
Lung cancer is the most common cancer in the world, either in terms of incidence or mortality, and it is still increasing in particular in the developing world and among women. The vast majority of lung cancers are due to tobacco smoking and therefore primary prevention through efficient tobacco control is possible. Occupational carcinogens are also recognised and the role of environmental exposures remains to be defined.

7. DOCID:30969 SCORE: 0.00239355205968118
DOCNO: 14584403
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Vaginal Smears
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: Deborah A Simon DA
AUTHOR: Elizabeth Dimitrievich E
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: South Dakota journal of medicine.
COUNTRY: United States
TITLE: Case report: detection of an advanced ovarian malignancy by cervical cytology.
PUBDATE: 20031001
There are currently no recommended screening tests for the early detection of ovarian cancer. Ovarian malignancies are most often discovered on bimanual exam at advanced stages, resulting in a high mortality from this disease. While the Papanicolaou (Pap) smear is not a reliable screen for the detection of ovarian cancer, abnormal cytology may be the initial indicator of ovarian malignancy. This is a case report of an invasive serous adenocarcinoma of the ovary that was discovered as the result of a clinical work-up for abnormal cytology reported on a Pap smear.

8. DOCID:26569 SCORE: 0.00236312403712832
DOCNO: 11292948
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: C Casali C
AUTHOR: A Stefani A
AUTHOR: M Paci M
AUTHOR: U Morandi U
AUTHOR: R Lodi R
AFFILIATION: Department of Cardio-Thoracic Surgery, University of Modena and Reggio Emilia, Modena, Italy.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of cardiovascular surgery.
COUNTRY: Italy
TITLE: Surgical management of solitary pulmonary nodules. An unexpected lucky case.
PUBDATE: 20010401
The case of a 63-year-old woman with a solitary pulmonary nodule (SPN) is reported. Surgical wedge resection revealed an hamartoma. Digital examination of the lung parenchyma showed an unexpected (not previously visualized by thoracic imaging) second nodule that intraoperative frozen examination revealed an adenocarcinoma. The operation was completed with a right upper lobectomy and complete lymphoadenectomy. The authors recommend an early open surgical procedure for any SPNs with risk factors for developing lung cancer.

9. DOCID:25583 SCORE: 0.00233922367853431
DOCNO: 11572037
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
QUALIFIER: metabolism
AUTHOR: M Kjellman M
AUTHOR: C Larsson C
AUTHOR: M Bäckdahl M
AFFILIATION: Department of Surgery, P9:03, Karolinska Hospital, S-17176, Stockholm, Sweden. kmak@kir.ks.sc
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: World journal of surgery.
COUNTRY: United States
TITLE: Genetic background of adrenocortical tumor development.
PUBDATE: 20010701
The increasing occurrence of incidentally discovered benign adrenocortical tumors has become a clinical dilemma because of the difficulties in differentiating them from their malignant counterpart. Adrenocortical tumors are associated with familial cancer syndromes such as the Beckwith-Wiedemann syndrome, the Li-Fraumeni syndrome, the Carney complex, multiple endocrine neoplasia type 1, congenital adrenal hyperplasia, and the McCune-Albright syndrome. Genetic events are known to take place on the chromosomal and gene level in sporadic adrenocortical tumors.

10. DOCID:25638 SCORE: 0.00233922343363719
DOCNO: 16329548
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: virology
QUALIFIER: complications
QUALIFIER: virology
QUALIFIER: virology
AUTHOR: B S Menon BS
AUTHOR: W M Wan Maziah WM
AFFILIATION: Department of Paediatrics, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia. radi@tm.net.my
PUBTYPE: Journal Article
JOURNALTITLE: The Malaysian journal of pathology.
COUNTRY: Malaysia
TITLE: Herpes zoster in children with cancer.
PUBDATE: 20010601
The aim of this study was to determine the incidence and outcome of herpes zoster hospitalised children with cancer in Kota Baru. It was a retrospective review from January 1994 to December 1998. The diagnosis of herpes zoster was a clinical one. Herpes zoster was diagnosed in 10 of 188 (5%) children with malignancy. The most common malignancy was leukaemia. Nine children were treated with acyclovir. No child developed visceral dissemination and there were no deaths.

11. DOCID:26743 SCORE: 0.00227902849383394
DOCNO: 11705003
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: therapy
QUALIFIER: genetics
AUTHOR: M D Ringel MD
AFFILIATION: Section of Endocrinology, Washington Hospital Center, 110 Irving Street, NW Room 2A46B, Washington, DC 20010, USA. mxr9@mhg.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Reviews in endocrine & metabolic disorders.
COUNTRY: United States
TITLE: Molecular diagnostic tests in the diagnosis and management of thyroid carcinoma.
PUBDATE: 20000401
The application of molecular analysis of gene expression to clinical tissue samples represents one of the most exciting new areas in "translational" thyroid cancer research. Current data suggest that molecular diagnostic assays may improve the sensitivity and accuracy of fine needle aspiration of thyroid nodules, fine needle aspiration of metastases, and detection of recurrent disease in peripheral blood samples. It is likely that at least some of these tests will become useful adjuncts in the diagnostic armamentarium of clinical endocrinologists in the future.

12. DOCID:26808 SCORE: 0.00227902173129779
DOCNO: 10696256
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
AUTHOR: D H Brown DH
AUTHOR: T T Wagner TT
AUTHOR: R R Bahnson RR
AFFILIATION: Division of Urology, Ohio State University, Columbus, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Urologic clinics of North America.
COUNTRY: UNITED STATES
TITLE: Interferons and bladder cancer.
PUBDATE: 20000201
With the introduction of BCG, intravesical instillation of immunotherapeutic agents has become a mainstay of therapy in the treatment of superficial bladder cancer. Interferon is capable of inducing a non-specific cellular and humoral immune response towards tumor cells. It has shown promise in reducing the recurrence and progression rates of superficial bladder cancer. In contrast to BCG, intravesical interferon is associated with minimal side effects and a very low dropout rate. Current research has focused on the use of interferon in combination with immunotherapeutic and cytotoxic drugs.

13. DOCID:27142 SCORE: 0.00226521631694253
DOCNO: 11474611
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Emergency Medical Services
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: I V Komisarenko IV
AUTHOR: S I Rybakov SI
AUTHOR: M M Bahirov MM
AUTHOR: Iu H Bondarenko IuH
AUTHOR: A I Sheptukha AI
PUBTYPE: Journal Article
JOURNALTITLE: Klinichna khirurhiia / Ministerstvo okhorony zdorov'ia Ukraïny, Naukove tovarystvo khirurhiv Ukraïny.
COUNTRY: Ukraine
TITLE: [Urgent interventions for invasive thyroidal carcinoma]
PUBDATE: 20000901
There was summarized the experience of treatment of the thyroid gland cancer, invading trachea (larynx) and other neighboring structures of the neck in 42 patients, whose state was estimated as severe one and neoplastic process--as nonoperable. Optimal surgical methods were applied depending on clinical signs of thyroidal carcinoma. In 36 patients the palliative resection of thyroid gland (in 6--with tracheostomy addition) was done, in 6--intervention was restricted by tracheostomy formation. The method of tracheostomy formation in cases of massive spreading of tumor along trachea is adduced.

14. DOCID:27973 SCORE: 0.0022473830392064
DOCNO: 11715303
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
AUTHOR: G Calais G
AUTHOR: E Asquier E
AUTHOR: P Louisot P
AFFILIATION: Clinique d'oncologie et radiothérapie, CHU, 2, boulevard Tonnellé, 37044 Tours, France. calais@med.univ-tours.fr
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Cancer radiothérapie : journal de la Société française de radiothérapie oncologique.
COUNTRY: France
TITLE: [Gross tumor volume and clinical target volume: esophageal tumors]
PUBDATE: 20011001
The oesophagus is divided into four regions: cervical oesophagus, and intrathoracic oesophagus with an upper, mid- and lower thoracic portion. Cancer may occur on each of these regions. Computed tomography of the thorax and superior abdomen and endoscopic ultrasound are necessary for reliable staging. CT simulation allows accurate definition of tumour volume. GTV includes tumour volume and regional lymph nodes. CTV encompasses GTV plus a safety margin and lymph node areas considered to harbour potential microscopic disease. The extent of prophylactic lymph node irradiation depends on the anatomic location of the primary tumour.