0. DOCID:30439 SCORE: 0.00508556874274074
DOCNO: 12117193
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: methods
QUALIFIER: methods
AUTHOR: Susan M Ascher SM
AUTHOR: Caroline Reinhold C
AFFILIATION: Department of Radiology, Georgetown University Hospital, Washington, DC 20007-2197, USA. aschers@gunet.georgetown.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Radiologic clinics of North America.
COUNTRY: United States
TITLE: Imaging of cancer of the endometrium.
PUBDATE: 20020501
Transvaginal US is often the initial imaging examination for women with dysfunctional (postmenopausal or intermenstrual) uterine bleeding. However, once the diagnosis of endometrial cancer has been made, contrast-enhanced MRI should be performed in patients who require multifactorial assessment (eg, depth of myometrial invasion, cervical involvement, lymph node metastasis). The results of contrast-enhanced MRI help distinguish patients who need more aggressive therapy and referral to a gynecologic oncologist from those who will do well treated by a community gynecologist.

1. DOCID:31684 SCORE: 0.00347501870498315
DOCNO: 12735680
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemical synthesis
QUALIFIER: pharmacology
QUALIFIER: chemical synthesis
QUALIFIER: chemical synthesis
QUALIFIER: pharmacology
AUTHOR: Sang Kook Lee SK
AUTHOR: Kyung Ae Nam KA
AUTHOR: Yeon Hoi Hoe YH
AUTHOR: Hye-Young Min HY
AUTHOR: Eun-Young Kim EY
AUTHOR: Hyojin Ko H
AUTHOR: Soyoung Song S
AUTHOR: Taeho Lee T
AUTHOR: Sanghee Kim S
AFFILIATION: College of Pharmacy, Ewha Womans University, 11-1 Daehyun-dong, Seodaemun-ku, Seoul 120-750, Korea. sklee@ewha.ac.kr
PUBTYPE: Journal Article
JOURNALTITLE: Archives of pharmacal research.
COUNTRY: Korea (South)
TITLE: Synthesis and evaluation of cytotoxicity of stilbene analogues.
PUBDATE: 20030401
Resveratrol analogs were newly synthesized and evaluated for cytotoxicity in cultured human lung and colon cancer cells. 3,5,4-Trimethoxy-trans-stilbene and 3,5,2',4'-tetramethoxy-trans-stilbene were found to be more potent rather than resveratrol. 3,4,5-Trimethoxy-4'-bromo-cis-stilbene was the most active among the test compounds.

2. DOCID:25519 SCORE: 0.00345466236987213
DOCNO: 11394005
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Liver Transplantation
QUALIFIER: pathology
QUALIFIER: secondary
QUALIFIER: surgery
AUTHOR: K Urata K
AUTHOR: S Kawasaki S
AFFILIATION: First Department of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.
PUBTYPE: Journal Article
JOURNALTITLE: Nippon Geka Gakkai zasshi.
COUNTRY: Japan
TITLE: [Liver transplantation for liver metastases of colorectal cancer]
PUBDATE: 20010501
Because of the critical shortage of donor organs, liver transplantation for metastatic tumors should be reserved for patients in whom long-term survival is possible. Transplantation in patients with metastatic tumors from colorectal cancer has resulted only in short disease-free intervals, and palliation was achieved in only a few patients. In patients with symptomatic neuroendocrine tumors unresponsive to conventional therapy, on the other hand, reasonably good disease-free intervals and prolonged survival may justify liver transplantation.

3. DOCID:27943 SCORE: 0.00331663026016405
DOCNO: 10559547
AUTHOR: D W Lamson DW
AUTHOR: M S Brignall MS
AFFILIATION: Tahoma Clinic, Kent, WA, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Alternative medicine review : a journal of clinical therapeutic.
COUNTRY: UNITED STATES
TITLE: Antioxidants in cancer therapy; their actions and interactions with oncologic therapies.
PUBDATE: 19991001
There is a concern that antioxidants might reduce oxidizing free radicals created by radiotherapy and some forms of chemotherapy, and thereby decrease the effectiveness of the therapy. The question has arisen whether concurrent administration of oral antioxidants is contraindicated during cancer therapeutics. Evidence reviewed here demonstrates exogenous antioxidants alone produce beneficial effects in various cancers, and except for a few specific cases, animal and human studies demonstrate no reduction of efficacy of chemotherapy or radiation when given with antioxidants. In fact, considerable data exists showing increased effectiveness of many cancer therapeutic agents, as well as a decrease in adverse effects, when given concurrently with antioxidants.

4. DOCID:31428 SCORE: 0.00295415418466382
DOCNO: 12676579
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: therapy
AUTHOR: Gillian Payne G
AFFILIATION: ImmunoGen Inc, 128 Sidney Street, Cambridge, MA 02139, USA. gillian.payne@immunogen.com
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Cancer cell.
COUNTRY: United States
TITLE: Progress in immunoconjugate cancer therapeutics.
PUBDATE: 20030301
Advances in immunoconjugate technology have revitalized the "magic bullet" concept of immunotherapeutics for the treatment of cancer. The growing availability of "human" antibodies, the increased epitope repertoire due to genomics and proteomics efforts, and advances in the means of identification and production of tumor-specific antibodies have greatly increased the potential for cancer therapeutic opportunities. Furthermore, the realization that effector molecule potency must be sufficiently high to be effective at concentrations that might realistically be delivered to the tumor site on an antibody carrier has greatly spurred the fields of medicinal chemistry and radionuclide chelate chemistry to produce such molecules.

5. DOCID:30996 SCORE: 0.00292085068538231
DOCNO: 12146015
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: adverse effects
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: Koji Kawai K
AFFILIATION: Dept. of Urology, Institute of Clinical Medicine, University of Tsukuba.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: Japan
TITLE: [Long-term side effects of chemotherapy for testicular cancer]
PUBDATE: 20020701
Since the advent of cisplatin-based chemotherapy in the 1970s, a majority of metastatic testicular cancer patients have been cured with chemotherapy and surgery. The high curability of testicular cancer, along with the young age of afflicted patients, can result in patients living for many years after the chemotherapy. Thus, the assessment of late effects of chemotherapy is clinically important in testicular cancer patients. This article summarizes the literature regarding the long-term side effects, and reviews approaches to the amelioration of these side effects.

6. DOCID:27835 SCORE: 0.00282087027839273
DOCNO: 11225056
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pharmacology
QUALIFIER: adverse effects
QUALIFIER: drug effects
QUALIFIER: radiation effects
QUALIFIER: drug effects
AUTHOR: T T Puck TT
AUTHOR: R Johnson R
AUTHOR: P Webb P
AFFILIATION: Eleanor Roosevelt Institute, 1899 Gaylord Street, Denver, Colorado 80206, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Somatic cell and molecular genetics.
COUNTRY: United States
TITLE: Mutation inhibition by beta-estradiol after low doses of gamma-irradiation of mammalian cells.
PUBDATE: 19990301
The methodology previously described for measuring mutagenesis has been applied to the study of mutation prevention in immortalized G2 phase human lymphocytes exposed to 25 and 50 cGy of gamma-radiation. Caffeine prevents repair of mutations. Two times 10(-4) M beta-estradiol applied for 2.5 h markedly decreases induced mutations and affects male and female cells similarly. Quantitative measurement of mutagenesis in cells of different individuals and the effect of various agents on mutation yield should be important in prevention of cancer and other mutational disease.

7. DOCID:24955 SCORE: 0.0028155324793371
DOCNO: 9555537
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
AUTHOR: H Wagner H
AFFILIATION: Thoracic Oncology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in oncology.
COUNTRY: UNITED STATES
TITLE: Enhancing the role of radiotherapy in non-small cell lung cancer.
PUBDATE: 19980301
Radiation therapy plays an important role in the treatment of patients with unresectable non-small cell lung cancer. Local control rates with past radiation therapy techniques have been poor, in the range of 10% to 15%. Recent advances in dose planning and delivery, as well as radiation biology, offer the promise of improved control and better protection of dose limiting normal tissues.

8. DOCID:24953 SCORE: 0.00281553209284645
DOCNO: 9679589
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: classification
AUTHOR: A Kaneko A
AFFILIATION: Division of Ophthalmology, National Cancer Center, Tokyo, Japan.
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [TNM classification of ophthalmic malignant tumors]
PUBDATE: 19980701
The present TNM classification of ophthalmic malignant tumors (lid cancer, malignant melanoma of the lid, conjunctival cancer, conjunctival malignant melanoma, uveal malignant melanoma, retinoblastoma, orbital sarcoma and lacrimal gland cancer) has been explained according to the UICC in a book edited by M. H. Harmer and J. A. Oosterhuis. Five studies concerning the difference in clinical results with and without a treatment were shown to confirm the meaning and importance of TNM classification of ophthalmic malignancies.

9. DOCID:25756 SCORE: 0.00273757188803295
DOCNO: 10452165
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Gene Expression Regulation, Neoplastic
QUALIFIER: genetics
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: A M Rich AM
AUTHOR: D Kerdpon D
AUTHOR: P C Reade PC
AFFILIATION: Department of Stomatology, School of Dentistry, University of Otago, New Zealand.
PUBTYPE: Journal Article
JOURNALTITLE: Australian dental journal.
COUNTRY: AUSTRALIA
TITLE: p53 expression in oral precancer and cancer.
PUBDATE: 19990601
Expression of the p53 tumour suppressor gene is a frequent finding in human malignancies, including oral cancer, and it has been detected in some potentially malignant lesions. The results of the present project showed that 35 of the 41 (85 per cent) oral mucosal lesions with histological evidence of epithelial dysplasia expressed p53, but the presence or absence of p53 staining could not be used to predict the outcome of potentially malignant oral mucosal lesions.

10. DOCID:30582 SCORE: 0.00248249802693426
DOCNO: 12594770
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: adverse effects
QUALIFIER: chemically induced
QUALIFIER: adverse effects
AUTHOR: James Melius J
AFFILIATION: Laborers' Health and Safety Fund of North America, 905 16th St. NW, Washington, DC 20006, USA. Melius@nysliuna.org
PUBTYPE: Journal Article
JOURNALTITLE: American journal of industrial medicine.
COUNTRY: United States
TITLE: Asphalt--a continuing challenge.
PUBDATE: 20030301
Assessing the health risks of complex mixtures of polynuclear aromatic hydrocarbons such as diesel fumes and asphalt or bitumen continues to be a major challenge for occupational and environmental health scientists. The special Asphalt issue of the American Journal of Industrial Medicine (Cancer Mortality Among European Asphalt Workers (Am.J.Ind.Med. Volume 43, Number 1, 2003) presented the results of a major multi-country epidemiological study of a group of workers exposed to one common commercial PAH mixture, asphalt or bitumen.

11. DOCID:30327 SCORE: 0.00248248570458535
DOCNO: 16283154
OWNER: NLM
STATUS: In-Process
AUTHOR: S Krege S
AFFILIATION: Urologie, Universitätsklinikum Essen. susanne.krege@uni-essen.de
PUBTYPE: Journal Article
JOURNALTITLE: Der Urologe. Ausg. A.
COUNTRY: Germany
TITLE: [Study landscape testicular cancer]
PUBDATE: 20051201
Testicular cancer is one of the few tumors which are curable even at an advanced stage. This has been achieved both by the use of platinum based chemotherapy and by the interdisciplinary approach by urologists, internal oncologists and radio-oncologists. In 1988, the Interdisciplinary Testicular Cancer Study Group was founded. The aim of this group is to initiate clinical trials to improve the results in the treatment of this tumor. Furthermore, the group has published evidenced-based national and international guidelines for testicular cancer. This article gives an overview on the work of the group including current studies.

12. DOCID:29850 SCORE: 0.00248248182285831
DOCNO: 16224561
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: enzymology
QUALIFIER: metabolism
AUTHOR: A M Shcherbakov AM
AUTHOR: E S Gershtein ES
AUTHOR: O A Anurova OA
AUTHOR: N E Kushlinskii NE
AFFILIATION: N. N. Blokhin Russian Oncological Research Center, Russian Academy of Medical Sciences, Moscow. cesaro@front.ru.
PUBTYPE: Journal Article
JOURNALTITLE: Bulletin of experimental biology and medicine.
COUNTRY: United States
TITLE: Activated proteinkinase B in breast cancer.
PUBDATE: 20050501
The content of activated (phosphorylated) form of proteinkinase B in tumors and homologous tissues of 46 patients with breast cancer was measured by enzyme immunoassay. Activity of proteinkinase B was increased in tumors of 48% patients in comparison with homologous histologically unchanged tissue. Activity of proteinkinase B in hormone-dependent mammary tumors was significantly higher than in tumor tissue from patients with negative receptor status.

13. DOCID:31824 SCORE: 0.00237730755809143
DOCNO: 12166850
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Algorithms
DESCRIPTOR: Computer Simulation
DESCRIPTOR: Models, Biological
QUALIFIER: diagnostic use
QUALIFIER: methods
QUALIFIER: methods
AUTHOR: Jennifer L Mueller JL
AUTHOR: Samuli Siltanen S
AUTHOR: David Isaacson D
AFFILIATION: Colorado State University, Fort Collins 80523, USA. mueller@math.colostate.edu
PUBTYPE: Journal Article
JOURNALTITLE: IEEE transactions on medical imaging.
COUNTRY: United States
TITLE: A direct reconstruction algorithm for electrical impedance tomography.
PUBDATE: 20020601
A direct (noniterative) reconstruction algorithm for electrical impedance tomography in the two-dimensional (2-D), cross-sectional geometry is reviewed. New results of a reconstruction of a numerically simulated phantom chest are presented. The algorithm is based on the mathematical uniqueness proof by A. I. Nachman [1996] for the 2-D inverse conductivity problem. In this geometry, several of the clinical applications include monitoring heart and lung function, diagnosis of pulmonary embolus, diagnosis of pulmonary edema, monitoring for internal bleeding, and the early detection of breast cancer.

14. DOCID:25462 SCORE: 0.00234332870415155
DOCNO: 11229082
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemically induced
QUALIFIER: drug effects
QUALIFIER: chemically induced
QUALIFIER: adverse effects
QUALIFIER: adverse effects
QUALIFIER: adverse effects
QUALIFIER: adverse effects
AUTHOR: C Magnusson C
AUTHOR: E Weiderpass E
AFFILIATION: Institutionen för medicinsk epidemiologi, Karolinska institutet, Stockholm. Cecilia.Magnusson@mep.ki.se
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Läkartidningen.
COUNTRY: Sweden
TITLE: [Hormone therapy in climacteric. Different effects of estrogen and gestagen on the risk of breast and endometrial cancer]
PUBDATE: 20010101
Use of hormone replacement therapy alleviates menopausal symptoms effectively, prevents osteoporosis and may even reduce the risk of cardiovascular disease and dementia. However, little is known about the risk of breast cancer and endometrial cancer after long-term use of different estrogen-progestin combinations. A large epidemiological study in Sweden, in which combined estrogen-progestin treatment was predominantly used, is reported.