The other Optex algorithms, PMAX, IESAFE, EMAX, can all be used for experiment design too. Generally they can't be trusted as well to explore an entire space. They sometimes settle on a good point and don't bother searching other areas. However, this can be a good feature if your search space is high dimensional and searching all of it is impractical. Also, IESAFE and EMAX can be useful if you already have some process data and prefer not to run any wild experiments with unpredictable, and likely poor, results.