SCDIFF

How to read the prediction results?

(1) Mouse over the node to show all the cell types for each node(state).
(2) Click the node to show: A. The enriched TFs for the node edge(edge: from its parent-> the node0); B. The enriched TFs for the whole path: (from root-> the node). C. Top differentially expressed genes for the node (from parent->the node).
D. Cells assigned to each node. (3) Search the TF in explore TF field. It will highlight the edges regulated by the searched TF and also display the expression of the TF.
(4) Search the Gene name in explore de field. It will highlight the edges in which the search gene is significantly up/down regulated. It also display the expression of the search gene.

Single Cell DataSets used in this study

Single Cell DataSets used in this study

Results

Note: Please read the HTML file within each result folder for detailed results.

Prediction result on Treutlein et al 2014 lung single cell dataset

Prediction result on Du et al 2015 lung single cell dataset

Prediction result on Treutlein et al 2016 mouse single cell dataset 1 (Ascl1 treated)

Prediction result on Treutlein et al 2016 mouse single cell dataset 2(Ascl1, Brn2 and Myt1l Ttreated)

Prediction result on Olsson et al. mouse bone marrow single cell dataset

Prediction result on Nestorowa et al. mouse hematopoietic single cell dataset

Prediction result on a large simulated dataset with 15k cells